thumbbandit, I've always had the feeling that the headache thing with the Virtual Boy was overblown. Most likely, a segment of the system's player population suffered from it, but they were a minority--which happened to be vocal. The same thing will probably happen with the 3DS, but likely to a lesser extent due to the different implementation.
sp3c, the motion sickness thing with first-person shooters is not something you just have to get used to. Some people, like me, will never be able to get over it. The problem is not strictly the first-person view but rather the 3D motion visuals not being coordinated with any of the other senses (primarily the sensations of gravity and acceleration). Recently, I played the original Spyro the Dragon on an HDTV and was quite ill afterward; to avoid the issue, I played it on the PSP, which was a very significant improvement. It's not the viewpoint, just the 3D movement (note that this paragraph has been referring to simple polygon-world 3D, not optical effect 3D). I still can't play a PC FPS, because the mouse-look controls change the on-screen view so rapidly => extreme motion sickness.
ZWG, I think few under-10 kids will get a 3DS; most parents are unlikely to spend $250 on children so young. The 3DS will still easily sell out, but its base of owners will skew older while it's at the launch price.
Does anyone here actually put their (non-Go) PSP into his pocket? I have a nice belt-mount pouch for my PSP that keeps it much safer than a pocket would. Personally, I would never even consider putting my PSP in a pocket.
On the subject of first-party software popularity, I disagree with JeremyR's stance that Sony doesn't have strong software. However, I get the feeling that he said "strong" when he really meant "as insanely popular as Halo," which is not the same thing.